Inhibition of CYP1A2 in liver microsomes (unknown origin) assessed as formation of acetaminophen from phenacetin in presence of NADPH by LC-MS/MS anal...

Basic Information

ID: ALA4018119

Type: ADME

Description: Inhibition of CYP1A2 in liver microsomes (unknown origin) assessed as formation of acetaminophen from phenacetin in presence of NADPH by LC-MS/MS analysis

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target: Cytochrome P450 1A2(ALA3356)

Document: ALA4017471

Inhibition of CYP1A2 in liver microsomes (unknown origin) assessed as formation of acetaminophen from phenacetin in presence of NADPH by LC-MS/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4018119

IC50

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
484.35	3.82	3.82

Parent Molecular Weight

ALogP

Polar Surface Area

484.35

3.82

Inhibition of CYP1A2 in liver microsomes (unknown origin) assessed as formation of acetaminophen from phenacetin in presence of NADPH by LC-MS/MS anal...

Basic Information

Activity Charts

Compound Summary