Basic Information
ID: ALA4018121
Type: ADME
Description: Inhibition of CYP2C19 in liver microsomes (unknown origin) assessed as formation of 4-hydroxymephenytoin from S-mephenytoin in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C19(ALA3622)
Document: ALA4017471
Inhibition of CYP2C19 in liver microsomes (unknown origin) assessed as formation of 4-hydroxymephenytoin from S-mephenytoin in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4018121
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 484.35 | 3.82 | 3.82 |