Basic Information
ID: ALA4018319
Type: ADME
Description: Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins in presence of NADPH by LC-MS/MS method
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4018319
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.39 | 6.80 | 6.80 |
| 436.42 | 1.83 | 1.83 |
| 456.45 | 4.53 | 4.53 |