Basic Information
ID: ALA4018519
Type: ADME
Description: Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate preincubated for 30 mins in presence of NADPH-generating system followed by substrate addition measured after 5 mins
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C8(ALA3721)
Document: ALA4017488
Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate preincubated for 30 mins in presence of NADPH-generating system followed by substrate addition measured after 5 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4018519
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.46 | 0.92 | 0.92 |