Basic Information
ID: ALA4018521
Type: ADME
Description: Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate preincubated for 2 to 40 mins followed by NADPH-generating system addition measured after 2 mins
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C8(ALA3721)
Document: ALA4017488
Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate preincubated for 2 to 40 mins followed by NADPH-generating system addition measured after 2 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4018521
Kinact
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.46 | 0.92 | 0.92 |