Basic Information
ID: ALA4019025
Type: Binding
Description: Inhibition of bacterial MBP-fused NDM1 expressed in Escherichia coli BL21(DE3) ausing chromacef as substrate preincubated for 20 mins followed by substrate addition measured after 0.3 mins
Organism: Bacteria
Activity Charts
Bioactivity
Activity Types for Assay ALA4019025
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 167.12 | 0.48 | 0.48 |
| 222.24 | 1.17 | 1.17 |
| 272.26 | 2.09 | 2.09 |
| 278.29 | 2.15 | 2.15 |
| 250.25 | 0.69 | 0.69 |
| 256.26 | 1.71 | 1.71 |
| 259.22 | 1.85 | 1.85 |
| 258.23 | 1.73 | 1.73 |
| 362.34 | 3.40 | 3.40 |
| 266.25 | 0.62 | 0.62 |
| 302.29 | 2.10 | 2.10 |
| 234.25 | 1.45 | 1.45 |
| 272.26 | 2.04 | 2.04 |
| 286.29 | 1.72 | 1.72 |
| 273.24 | 2.15 | 2.15 |
| 243.22 | 2.15 | 2.15 |
| 263.28 | 1.17 | 1.17 |
| 287.23 | 1.84 | 1.84 |
| 286.29 | 2.13 | 2.13 |
| 208.22 | 0.92 | 0.92 |
| 210.19 | 0.54 | 0.54 |
| 246.22 | 1.30 | 1.30 |
| 262.22 | 1.68 | 1.68 |
| 273.24 | 2.15 | 2.15 |
| 259.22 | 1.85 | 1.85 |
| 258.23 | 2.22 | 2.22 |
| 224.17 | -0.41 | -0.41 |
| 234.25 | 1.41 | 1.41 |
| 242.23 | 2.03 | 2.03 |
| 316.27 | 1.82 | 1.82 |
| 258.23 | 1.73 | 1.73 |
| 300.27 | 1.44 | 1.44 |
| 286.29 | 2.21 | 2.21 |
| 300.27 | 2.10 | 2.10 |
| 273.24 | 2.15 | 2.15 |
| 248.28 | 1.84 | 1.84 |
| 286.29 | 2.21 | 2.21 |
| 270.29 | 1.75 | 1.75 |
| 288.26 | 2.23 | 2.23 |
| 201.56 | 1.13 | 1.13 |
| 262.29 | 1.77 | 1.77 |
| 276.32 | 1.81 | 1.81 |
| 259.22 | 1.85 | 1.85 |
| 376.37 | 3.33 | 3.33 |