Basic Information
ID: ALA4019404
Type: Binding
Description: Inhibition of P38 alpha MAPK in human whole blood assessed as reduction in TNF-alpha release after 10 mins by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4019404
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 592.67 | 5.21 | 5.21 |
| 457.51 | 4.15 | 4.15 |
| 529.52 | 5.79 | 5.79 |
| 616.69 | 5.41 | 5.41 |
| 505.52 | 4.11 | 4.11 |
| 535.55 | 3.47 | 3.47 |
| 502.52 | 5.79 | 5.79 |
| 457.51 | 4.61 | 4.61 |
| 571.58 | 4.37 | 4.37 |
| 577.61 | 4.43 | 4.43 |
| 517.56 | 3.33 | 3.33 |
| 523.56 | 4.87 | 4.87 |
| 579.58 | 4.23 | 4.23 |
| 557.60 | 5.48 | 5.48 |
| 575.62 | 4.40 | 4.40 |
| 453.54 | 4.32 | 4.32 |
| 600.67 | 5.07 | 5.07 |
| 541.55 | 5.66 | 5.66 |
| 529.59 | 4.93 | 4.93 |
| 609.61 | 3.59 | 3.59 |
| 489.50 | 3.76 | 3.76 |
| 516.55 | 6.10 | 6.10 |
| 545.97 | 6.30 | 6.30 |
| 531.57 | 4.73 | 4.73 |
| 567.62 | 4.54 | 4.54 |
| 481.48 | 5.04 | 5.04 |
| 500.55 | 6.00 | 6.00 |
| 455.56 | 4.57 | 4.57 |
| 494.52 | 5.94 | 5.94 |
| 485.54 | 5.31 | 5.31 |
| 460.46 | 4.83 | 4.83 |
| 618.66 | 5.21 | 5.21 |
| 579.58 | 4.23 | 4.23 |
| 487.51 | 5.11 | 5.11 |
| 493.54 | 5.51 | 5.51 |
| 559.62 | 4.30 | 4.30 |
| 453.54 | 4.78 | 4.78 |
| 541.55 | 5.01 | 5.01 |
| 459.52 | 4.40 | 4.40 |
| 579.58 | 4.23 | 4.23 |
| 561.59 | 4.09 | 4.09 |
| 503.53 | 5.45 | 5.45 |
| 518.54 | 6.14 | 6.14 |
| 469.59 | 4.91 | 4.91 |
| 556.64 | 4.31 | 4.31 |
| 496.49 | 5.73 | 5.73 |
| 457.51 | 4.61 | 4.61 |
| 610.66 | 5.35 | 5.35 |
| 457.51 | 4.15 | 4.15 |
| 574.63 | 4.45 | 4.45 |
| 529.52 | 5.79 | 5.79 |
| 520.51 | 5.93 | 5.93 |
| 547.58 | 5.07 | 5.07 |
| 553.59 | 4.23 | 4.23 |
| 461.47 | 4.49 | 4.49 |
| 594.64 | 5.01 | 5.01 |
| 453.54 | 4.32 | 4.32 |
| 541.55 | 5.66 | 5.66 |
| 545.97 | 6.30 | 6.30 |
| 479.51 | 5.25 | 5.25 |
| 556.64 | 4.31 | 4.31 |
| 519.53 | 3.12 | 3.12 |
| 511.53 | 5.65 | 5.65 |
| 475.50 | 4.75 | 4.75 |
| 505.50 | 5.24 | 5.24 |
| 453.54 | 4.78 | 4.78 |
| 598.70 | 5.27 | 5.27 |
| 497.50 | 5.39 | 5.39 |
| 579.53 | 6.67 | 6.67 |
| 459.52 | 4.40 | 4.40 |