ID: ALA4019414
Type: Binding
Description: Transactivation of human FXR expressed in human HeLa cells co-expressing BSEP at 50 uM after 24 hrs by dual-glo luciferase reporter gene assay relative to GW4064
Organism: Homo sapiens
Cell type: HeLa
Bioactivity
Activity Types for Assay ALA4019414
Emax
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
298.34 | 2.38 | 2.38 |
346.45 | 2.56 | 2.56 |
297.40 | 3.92 | 3.92 |
329.37 | 3.75 | 3.75 |
360.48 | 3.29 | 3.29 |
269.30 | 2.62 | 2.62 |
335.41 | 3.09 | 3.09 |
313.47 | 4.64 | 4.64 |
394.92 | 3.94 | 3.94 |
388.49 | 2.74 | 2.74 |
341.41 | 3.62 | 3.62 |
331.37 | 3.98 | 3.98 |
325.41 | 4.17 | 4.17 |
378.39 | 4.41 | 4.41 |
339.44 | 3.93 | 3.93 |
324.42 | 3.27 | 3.27 |
325.45 | 4.70 | 4.70 |
367.44 | 5.53 | 5.53 |
325.41 | 3.92 | 3.92 |
309.41 | 4.12 | 4.12 |
311.38 | 3.61 | 3.61 |
262.31 | 1.00 | 1.00 |
331.37 | 3.98 | 3.98 |
325.41 | 3.92 | 3.92 |
310.40 | 3.01 | 3.01 |
292.38 | 3.79 | 3.79 |
315.33 | 2.33 | 2.33 |
329.47 | 3.65 | 3.65 |
391.27 | 4.35 | 4.35 |
283.33 | 2.93 | 2.93 |
412.84 | 5.07 | 5.07 |
345.83 | 4.27 | 4.27 |
345.83 | 4.27 | 4.27 |
312.37 | 4.33 | 4.33 |
295.38 | 3.73 | 3.73 |
282.39 | 3.50 | 3.50 |
351.37 | 4.81 | 4.81 |
341.41 | 3.38 | 3.38 |
338.45 | 3.62 | 3.62 |
311.38 | 3.61 | 3.61 |
364.44 | 2.70 | 2.70 |
269.30 | 2.62 | 2.62 |
331.37 | 3.98 | 3.98 |
297.40 | 3.41 | 3.41 |
325.41 | 3.54 | 3.54 |
255.27 | 2.31 | 2.31 |
283.33 | 2.93 | 2.93 |
324.42 | 3.87 | 3.87 |
311.43 | 4.31 | 4.31 |
324.16 | 3.62 | 3.62 |
345.46 | 3.32 | 3.32 |
329.37 | 3.75 | 3.75 |
269.30 | 2.62 | 2.62 |
305.33 | 3.47 | 3.47 |
261.32 | 2.58 | 2.58 |