Basic Information
ID: ALA4019510
Type: ADME
Description: Drug metabolism in Sprague-Dawley rat liver microsomes assessed as 4-tert-butyl-N-(2-chloro-4-(methylsulfonamido)benzyl)-2-hydroxybenzamide formation at 10 uM preincubated with NADPH regenerating system for 5 mins followed by addition of liver microsomes by LC-MS/MS method
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4019510
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.92 | 3.94 | 3.94 |