Basic Information
ID: ALA4019532
Type: Binding
Description: Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins followed by ATP addition measured for 30 mins by pyruvate kinase-lactate dehydrogenase coupled enzyme assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4019532
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 214.15 | 2.35 | 2.35 |
| 217.27 | 1.41 | 1.41 |
| 310.28 | 2.41 | 2.41 |
| 399.42 | 1.05 | 1.05 |
| 171.56 | 1.33 | 1.33 |
| 413.44 | 1.30 | 1.30 |
| 246.31 | 1.48 | 1.48 |
| 310.28 | 2.41 | 2.41 |
| 338.33 | 2.98 | 2.98 |