Basic Information
ID: ALA4019549
Type: Functional
Description: In vivo inhibition of KHK-C in po dosed Sprague-Dawley rat assessed as decrease in F1P levels in kidney administered for 1 hr followed by bolus fructose administration measured 2 mins after iv infusion by LC/MS analysis
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Target: Rattus norvegicus(ALA376)
Document: ALA4017511
In vivo inhibition of KHK-C in po dosed Sprague-Dawley rat assessed as decrease in F1P levels in kidney administered for 1 hr followed by bolus fructose administration measured 2 mins after iv infusion by LC/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4019549
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.35 | 0.47 | 0.47 |