Basic Information
ID: ALA4019728
Type: Binding
Description: Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response administered for 12 secs followed by washout period for 181 secs by voltage clamp technique
Format: BAO_0000219
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA4017516
Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response administered for 12 secs followed by washout period for 181 secs by voltage clamp technique: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4019728
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 219.35 | 2.36 | 2.36 |
| 357.42 | 2.14 | 2.14 |
| 190.29 | 1.83 | 1.83 |