Basic Information
ID: ALA4019805
Type: Binding
Description: Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli at 30 uM after 30 mins using histone H3(1-21)K4(Me1) biotin peptide as substrate by TR-FRET assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Lysine-specific histone demethylase 1(ALA6136)
Document: ALA4017519
Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli at 30 uM after 30 mins using histone H3(1-21)K4(Me1) biotin peptide as substrate by TR-FRET assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4019805
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.44 | 3.30 | 3.30 |
| 580.71 | 2.55 | 2.55 |
| 481.58 | 1.61 | 1.61 |
| 412.52 | 2.01 | 2.01 |
| 452.54 | 3.46 | 3.46 |
| 376.50 | 3.07 | 3.07 |
| 380.47 | 2.90 | 2.90 |
| 438.55 | 2.27 | 2.27 |
| 440.57 | 2.61 | 2.61 |
| 440.53 | 3.21 | 3.21 |
| 405.50 | 1.86 | 1.86 |
| 452.54 | 1.59 | 1.59 |
| 398.49 | 1.62 | 1.62 |
| 348.45 | 2.51 | 2.51 |
| 412.52 | 2.01 | 2.01 |
| 396.47 | 2.66 | 2.66 |
| 410.50 | 1.63 | 1.63 |
| 426.54 | 2.40 | 2.40 |
| 428.48 | 3.00 | 3.00 |
| 369.47 | 4.58 | 4.58 |
| 412.52 | 1.93 | 1.93 |
| 362.48 | 2.82 | 2.82 |
| 406.47 | 3.10 | 3.10 |
| 481.58 | 1.61 | 1.61 |
| 410.49 | 2.91 | 2.91 |
| 396.92 | 3.42 | 3.42 |
| 412.52 | 2.01 | 2.01 |
| 391.45 | 2.53 | 2.53 |
| 405.50 | 1.86 | 1.86 |
| 438.55 | 2.27 | 2.27 |
| 426.54 | 2.27 | 2.27 |
| 398.49 | 1.62 | 1.62 |
| 422.50 | 2.92 | 2.92 |
| 402.50 | 2.40 | 2.40 |