Basic Information
ID: ALA4019946
Type: Binding
Description: Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic assay
Format: BAO_0000219
Organism: Homo sapiens
Target: p53-binding protein Mdm-2(ALA5023)
Document: ALA4017523
Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4019946
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.50 | 5.89 | 5.89 |
| 428.87 | 4.10 | 4.10 |
| 479.58 | 5.60 | 5.60 |
| 599.73 | 6.50 | 6.50 |
| 461.56 | 4.27 | 4.27 |
| 388.47 | 3.60 | 3.60 |
| 373.45 | 4.02 | 4.02 |
| 403.48 | 3.81 | 3.81 |
| 389.45 | 3.73 | 3.73 |
| 445.56 | 5.20 | 5.20 |
| 407.90 | 4.67 | 4.67 |
| 523.63 | 5.30 | 5.30 |
| 418.45 | 3.93 | 3.93 |
| 389.45 | 3.73 | 3.73 |
| 479.58 | 5.02 | 5.02 |