Basic Information
ID: ALA4020316
Type: ADME
Description: Inhibition of cytoplasmic LeuRS in human HepG2 cells assessed as reduction in protein synthesis preincubated for 48 hrs followed by L-[14C]leucine addition measured after 3 hrs by liquid scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4020316
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 263.92 | ||
| 336.38 | ||
| 285.93 | ||
| 277.94 | ||
| 338.39 | ||
| 293.94 | ||
| 308.37 | ||
| 291.93 |