Basic Information
ID: ALA4021025
Type: Binding
Description: Inhibition of rat Cav1.2 expressed in human tsA-201 cells co-expressing Cavbeta1b/Cavalpha2delta1 assessed as tonic block at 10 uM at holding potential of -90 mV by whole cell patch clamp method relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4021025
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 548.56 | 3.27 | 3.27 |
| 466.49 | 3.20 | 3.20 |
| 576.57 | 3.11 | 3.11 |
| 391.38 | 2.06 | 2.06 |
| 419.43 | 2.84 | 2.84 |
| 391.38 | 0.88 | 0.88 |
| 405.41 | 2.45 | 2.45 |
| 480.52 | 3.55 | 3.55 |
| 376.37 | 1.37 | 1.37 |
| 377.35 | 1.97 | 1.97 |
| 435.43 | 2.08 | 2.08 |
| 556.62 | 4.84 | 4.84 |
| 415.40 | 2.06 | 2.06 |
| 358.35 | 2.41 | 2.41 |