Basic Information
ID: ALA4021027
Type: Binding
Description: Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NBD-cAMP competition assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Rap guanine nucleotide exchange factor 3(ALA2029197)
Document: ALA4020713
Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NBD-cAMP competition assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4021027
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.78 | 3.80 | 3.80 |
| 399.67 | 5.11 | 5.11 |
| 350.76 | 4.17 | 4.17 |
| 342.72 | 3.79 | 3.79 |
| 448.79 | 5.20 | 5.20 |
| 436.75 | 5.33 | 5.33 |
| 474.87 | 6.49 | 6.49 |
| 344.25 | 3.42 | 3.42 |
| 324.73 | 3.66 | 3.66 |
| 340.73 | 3.76 | 3.76 |
| 453.21 | 5.84 | 5.84 |
| 452.31 | 5.55 | 5.55 |
| 392.72 | 4.67 | 4.67 |
| 408.72 | 4.78 | 4.78 |
| 368.76 | 4.31 | 4.31 |
| 380.79 | 4.18 | 4.18 |
| 418.76 | 5.19 | 5.19 |
| 474.87 | 6.49 | 6.49 |
| 342.72 | 3.79 | 3.79 |
| 392.72 | 4.67 | 4.67 |
| 406.87 | 5.47 | 5.47 |
| 482.34 | 5.56 | 5.56 |
| 385.21 | 4.82 | 4.82 |
| 474.87 | 6.49 | 6.49 |
| 426.28 | 5.04 | 5.04 |
| 392.72 | 4.67 | 4.67 |
| 408.72 | 4.78 | 4.78 |
| 486.76 | 6.21 | 6.21 |
| 436.75 | 5.33 | 5.33 |
| 418.76 | 5.19 | 5.19 |
| 508.42 | 6.85 | 6.85 |