Basic Information
ID: ALA4021028
Type: Binding
Description: Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NBD-cAMP competition assay
Format: BAO_0000357
Organism: Mus musculus
Target: Rap guanine nucleotide exchange factor 4(ALA3593151)
Document: ALA4020713
Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NBD-cAMP competition assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4021028
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.78 | 3.80 | 3.80 |
| 448.79 | 5.20 | 5.20 |
| 452.31 | 5.55 | 5.55 |
| 392.72 | 4.67 | 4.67 |
| 408.72 | 4.78 | 4.78 |
| 474.87 | 6.49 | 6.49 |
| 392.72 | 4.67 | 4.67 |
| 482.34 | 5.56 | 5.56 |
| 392.72 | 4.67 | 4.67 |
| 408.72 | 4.78 | 4.78 |
| 418.76 | 5.19 | 5.19 |