Basic Information
ID: ALA4021718
Type: Binding
Description: Chaperone activity at FLAG/GFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as increase in localization of protein mutant in late endosomes after 24 hrs by Hoechst 33342 staining based fluorescence microscopic analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4021718
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.33 | 3.66 | 3.66 |
| 281.36 | 3.45 | 3.45 |
| 295.38 | 4.01 | 4.01 |
| 293.37 | 4.16 | 4.16 |
| 294.35 | 3.05 | 3.05 |
| 308.38 | 3.31 | 3.31 |
| 322.41 | 3.66 | 3.66 |
| 382.46 | 2.38 | 2.38 |
| 312.41 | 3.17 | 3.17 |
| 547.82 | 5.44 | 5.44 |
| 282.30 | 1.25 | 1.25 |
| 280.33 | 2.83 | 2.83 |
| 336.44 | 4.22 | 4.22 |
| 280.33 | 2.66 | 2.66 |
| 308.38 | 3.91 | 3.91 |
| 252.27 | 1.79 | 1.79 |
| 308.38 | 3.44 | 3.44 |
| 308.38 | 3.44 | 3.44 |
| 296.33 | 1.90 | 1.90 |
| 322.41 | 3.83 | 3.83 |
| 344.44 | 3.33 | 3.33 |
| 298.39 | 2.78 | 2.78 |
| 278.31 | 2.44 | 2.44 |
| 266.30 | 2.27 | 2.27 |
| 334.42 | 3.83 | 3.83 |
| 368.51 | ||
| 308.38 | 3.44 | 3.44 |
| 308.38 | 3.44 | 3.44 |