Basic Information
ID: ALA4022061
Type: Binding
Description: Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4022061
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.41 | 0.42 | 0.42 |
| 396.42 | 1.38 | 1.38 |
| 412.88 | 2.28 | 2.28 |
| 395.43 | 2.83 | 2.83 |
| 396.42 | 1.77 | 1.77 |
| 405.50 | 3.15 | 3.15 |
| 408.46 | 1.64 | 1.64 |
| 387.44 | 1.47 | 1.47 |
| 377.44 | 2.69 | 2.69 |
| 378.43 | 1.63 | 1.63 |
| 396.42 | 1.77 | 1.77 |
| 391.47 | 2.90 | 2.90 |
| 454.53 | 3.30 | 3.30 |
| 377.44 | 3.03 | 3.03 |
| 377.44 | 2.69 | 2.69 |
| 393.44 | 2.35 | 2.35 |
| 391.47 | 2.76 | 2.76 |
| 402.45 | 1.36 | 1.36 |