Basic Information
ID: ALA4022511
Type: Functional
Description: Antiinflammatory activity in primary human endothelial keratinocytes assessed as inhibition of IL-17A/TNF-alpha induced IL-8 production at 10 uM preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by HTRF assay relative to control
Organism: Homo sapiens
Cell type: Keratinocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA4022511
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.47 | 1.90 | 1.90 |
| 234.34 | 3.79 | 3.79 |
| 341.47 | 5.16 | 5.16 |
| 323.48 | 5.02 | 5.02 |
| 355.50 | 5.20 | 5.20 |
| 341.47 | 5.16 | 5.16 |
| 303.49 | 4.87 | 4.87 |
| 341.47 | 5.16 | 5.16 |
| 291.44 | 3.47 | 3.47 |
| 416.40 | 5.83 | 5.83 |
| 337.51 | 5.06 | 5.06 |
| 346.52 | 3.15 | 3.15 |
| 338.50 | 4.46 | 4.46 |