Antiinflammatory activity in human whole blood assessed as inhibition of LPS-induced TNF-alpha release preincubated for 1 hr followed by LPS addition ...

Basic Information

ID: ALA4022532

Type: Functional

Description: Antiinflammatory activity in human whole blood assessed as inhibition of LPS-induced TNF-alpha release preincubated for 1 hr followed by LPS addition after 3.5 hrs by ELISA method

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Blood

Target: Blood(ALA613416)

Document: ALA4020802

Antiinflammatory activity in human whole blood assessed as inhibition of LPS-induced TNF-alpha release preincubated for 1 hr followed by LPS addition after 3.5 hrs by ELISA method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4022532

IC50

Total(32)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
570.61	2.48	2.48
406.40	1.84	1.84
392.37	1.53	1.53
407.39	1.11	1.11
392.37	1.53	1.53
460.37	2.55	2.55
536.56	2.20	2.20
391.39	1.03	1.03
424.39	1.97	1.97
391.39	1.26	1.26
420.43	2.14	2.14
458.43	1.71	1.71
417.38	1.40	1.40
393.36	0.92	0.92
449.42	0.89	0.89
458.43	1.92	1.92
407.39	1.11	1.11
476.45	1.06	1.06
556.58	2.14	2.14
406.40	1.84	1.84
391.38	2.13	2.13
526.41	0.86	0.86
397.42	1.10	1.10
392.37	1.53	1.53
410.36	1.67	1.67
392.38	0.43	0.43
408.37	1.23	1.23
508.47	0.60	0.60
516.49	2.62	2.62
476.49	0.94	0.94
458.43	1.92	1.92
460.37	2.55	2.55