Basic Information
ID: ALA4022608
Type: Binding
Description: Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced calcium influx at 3 uM preincubated for 6 mins followed by AITC addition measured for 1 min by Fluo-4 dye-based assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Transient receptor potential cation channel subfamily A member 1(ALA6007)
Document: ALA4020807
Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced calcium influx at 3 uM preincubated for 6 mins followed by AITC addition measured for 1 min by Fluo-4 dye-based assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4022608
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 228.25 | 2.97 | 2.97 |
| 228.25 | 2.97 | 2.97 |
| 230.26 | 2.59 | 2.59 |
| 283.58 | 5.82 | 5.82 |
| 196.25 | 3.56 | 3.56 |
| 246.69 | 3.92 | 3.92 |
| 370.04 | 4.79 | 4.79 |
| 249.14 | 5.16 | 5.16 |
| 259.26 | 2.36 | 2.36 |