Basic Information
ID: ALA4022615
Type: Binding
Description: Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced calcium influx at 30 uM preincubated for 6 mins followed by AITC addition measured for 1 min by Fluo-4 dye-based assay relative to resveratrol
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Transient receptor potential cation channel subfamily A member 1(ALA6007)
Document: ALA4020807
Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced calcium influx at 30 uM preincubated for 6 mins followed by AITC addition measured for 1 min by Fluo-4 dye-based assay relative to resveratrol: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4022615
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.33 | 3.88 | 3.88 |
| 242.27 | 3.28 | 3.28 |
| 244.25 | 2.68 | 2.68 |
| 212.25 | 3.27 | 3.27 |
| 228.25 | 2.97 | 2.97 |
| 228.25 | 2.97 | 2.97 |
| 230.26 | 2.59 | 2.59 |
| 283.58 | 5.82 | 5.82 |
| 240.30 | 3.87 | 3.87 |
| 226.28 | 3.57 | 3.57 |
| 196.25 | 3.56 | 3.56 |
| 272.30 | 3.29 | 3.29 |
| 202.21 | 2.47 | 2.47 |
| 354.36 | 3.63 | 3.63 |
| 214.69 | 4.51 | 4.51 |
| 260.25 | 2.39 | 2.39 |
| 196.25 | 3.56 | 3.56 |
| 210.28 | 3.87 | 3.87 |
| 245.23 | 2.06 | 2.06 |
| 228.25 | 2.97 | 2.97 |
| 246.69 | 3.92 | 3.92 |
| 270.33 | 4.06 | 4.06 |
| 370.04 | 4.79 | 4.79 |
| 324.42 | 5.23 | 5.23 |
| 318.37 | 4.85 | 4.85 |
| 218.30 | 3.69 | 3.69 |
| 360.41 | 3.81 | 3.81 |
| 312.41 | 5.23 | 5.23 |
| 386.04 | 4.50 | 4.50 |
| 256.26 | 3.00 | 3.00 |
| 249.14 | 5.16 | 5.16 |
| 259.26 | 2.36 | 2.36 |
| 312.41 | 5.05 | 5.05 |
| 192.26 | 3.16 | 3.16 |
| 354.49 | 6.22 | 6.22 |
| 256.30 | 3.67 | 3.67 |
| 262.31 | 4.42 | 4.42 |