Agonist activity at human TRPA1 expressed in HEK293 cells assessed as induction of calcium influx at 30 uM after 6 mins by Fluo-4 dye-based assay rela...

Basic Information

ID: ALA4022616

Type: ADME

Description: Agonist activity at human TRPA1 expressed in HEK293 cells assessed as induction of calcium influx at 30 uM after 6 mins by Fluo-4 dye-based assay relative to AITC

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Transient receptor potential cation channel subfamily A member 1(ALA6007)

Document:  ALA4020807

Agonist activity at human TRPA1 expressed in HEK293 cells assessed as induction of calcium influx at 30 uM after 6 mins by Fluo-4 dye-based assay relative to AITC: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
270.333.883.88
242.273.283.28
228.252.972.97
244.252.682.68
212.253.273.27
228.252.972.97
228.252.972.97
230.262.592.59
283.585.825.82
240.303.873.87
226.283.573.57
196.253.563.56
272.303.293.29
202.212.472.47
354.363.633.63
214.694.514.51
260.252.392.39
196.253.563.56
210.283.873.87
245.232.062.06
228.252.972.97
246.693.923.92
270.334.064.06
370.044.794.79
324.425.235.23
318.374.854.85
218.303.693.69
360.413.813.81
312.415.235.23
386.044.504.50
256.263.003.00
249.145.165.16
259.262.362.36
312.415.055.05
192.263.163.16
354.496.226.22
256.303.673.67
262.314.424.42