Basic Information
ID: ALA4022773
Type: Binding
Description: Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substrate assessed as decrease in IMP levels after 1 hr by mass spectrometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4022773
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.47 | 0.35 | 0.35 |
| 409.46 | 2.10 | 2.10 |
| 445.44 | 2.35 | 2.35 |
| 409.46 | 2.10 | 2.10 |
| 417.44 | 2.88 | 2.88 |
| 423.49 | 2.49 | 2.49 |
| 341.35 | 1.18 | 1.18 |
| 423.49 | 2.49 | 2.49 |
| 427.45 | 2.05 | 2.05 |
| 258.30 | 2.36 | 2.36 |
| 447.51 | 3.42 | 3.42 |
| 343.34 | 2.34 | 2.34 |
| 445.44 | 2.35 | 2.35 |
| 325.35 | 2.20 | 2.20 |
| 427.45 | 2.05 | 2.05 |
| 301.33 | 1.46 | 1.46 |
| 461.54 | 3.81 | 3.81 |
| 423.49 | 2.49 | 2.49 |
| 336.76 | 2.02 | 2.02 |