In vivo inhibition of AICARFT in tumor of low folate diet fed nude mouse xenografted with human NCI-H460 cells assessed as increase in intratumoral ZM...

Basic Information

ID: ALA4022803

Type: Functional

Description: In vivo inhibition of AICARFT in tumor of low folate diet fed nude mouse xenografted with human NCI-H460 cells assessed as increase in intratumoral ZMP levels at 0.3 to 30 mg/kg after 4 hrs relative to vehicle-treated control

Format: BAO_0000218

Organism: Mus musculus

Target: Mus musculus(ALA375)

Document: ALA4020815

In vivo inhibition of AICARFT in tumor of low folate diet fed nude mouse xenografted with human NCI-H460 cells assessed as increase in intratumoral ZMP levels at 0.3 to 30 mg/kg after 4 hrs relative to vehicle-treated control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4022803

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
409.46	2.10	2.10
427.45	2.05	2.05
445.44	2.35	2.35

Parent Molecular Weight

ALogP

Polar Surface Area

409.46

2.10

427.45

2.05

445.44

2.35

In vivo inhibition of AICARFT in tumor of low folate diet fed nude mouse xenografted with human NCI-H460 cells assessed as increase in intratumoral ZM...

Basic Information

Activity Charts

Compound Summary