Basic Information
ID: ALA4022803
Type: Functional
Description: In vivo inhibition of AICARFT in tumor of low folate diet fed nude mouse xenografted with human NCI-H460 cells assessed as increase in intratumoral ZMP levels at 0.3 to 30 mg/kg after 4 hrs relative to vehicle-treated control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4022803
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.46 | 2.10 | 2.10 |
| 427.45 | 2.05 | 2.05 |
| 445.44 | 2.35 | 2.35 |