In vivo inhibition of AICARFT in tumor of low folate diet fed nude mouse xenografted with human NCI-H460 cells assessed as increase in circulating AIC...

Basic Information

ID: ALA4022804

Type: Functional

Description: In vivo inhibition of AICARFT in tumor of low folate diet fed nude mouse xenografted with human NCI-H460 cells assessed as increase in circulating AICAr levels at 0.3 to 30 mg/kg after 4 hrs relative to vehicle-treated control

Format: BAO_0000218

Organism: Mus musculus

Target:  Mus musculus(ALA375)

Document:  ALA4020815

In vivo inhibition of AICARFT in tumor of low folate diet fed nude mouse xenografted with human NCI-H460 cells assessed as increase in circulating AICAr levels at 0.3 to 30 mg/kg after 4 hrs relative to vehicle-treated control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
409.462.102.10
427.452.052.05
445.442.352.35