Basic Information
ID: ALA4022864
Type: Binding
Description: Allosteric enhancement of GAA p.R375L/p.V755SfsX41 mutant activity in pompe disease patient derived fibroblasts at 20 uM using 4-methylunbelliferyl alpha-D-glucopyranoside as substrate preincubated for 4 days followed by substrate addition measured after 60 mins in presence of recombinant human GAA by fluorometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4022864
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 219.28 | -1.45 | -1.45 |
| 219.28 | -1.45 | -1.45 |