Basic Information
ID: ALA4022894
Type: Binding
Description: Corrector activity at HRP-fused CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in matured protein levels at cell surface after 18 to 24 hrs by luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4022894
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.90 | 6.07 | 6.07 |
| 539.53 | 5.45 | 5.45 |
| 449.45 | 5.42 | 5.42 |
| 479.48 | 5.43 | 5.43 |
| 483.90 | 6.07 | 6.07 |
| 453.84 | 5.25 | 5.25 |
| 523.49 | 5.13 | 5.13 |
| 467.44 | 5.56 | 5.56 |
| 419.40 | 4.60 | 4.60 |
| 539.53 | 5.45 | 5.45 |
| 455.38 | 4.50 | 4.50 |
| 479.48 | 4.91 | 4.91 |
| 539.53 | 5.45 | 5.45 |
| 419.40 | 4.60 | 4.60 |
| 483.90 | 6.07 | 6.07 |