ID: ALA4022897
Type: Binding
Description: Corrector activity at CFTR F508del/F508del mutant in primary HBE cells assessed as increase in chloride ion current across apical membrane measured 18 to 24 hrs post compound treatment on basolateral side of cells in presence of channel potentiator GLPG1837 by trans-epithelial current clamp method
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4022897
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
452.41 | 4.75 | 4.75 |
523.49 | 5.13 | 5.13 |
561.46 | 6.14 | 6.14 |
511.45 | 5.26 | 5.26 |
523.49 | 5.13 | 5.13 |
539.53 | 5.45 | 5.45 |
559.47 | 5.72 | 5.72 |
479.48 | 4.91 | 4.91 |
523.49 | 5.13 | 5.13 |
559.47 | 5.72 | 5.72 |