Basic Information
ID: ALA4022973
Type: ADME
Description: Inhibition of JAK2 in CD34+ human whole blood assessed as reduction in EOP induced STAT5 phosphorylation preincubated for 45 mins followed by EOP addition measured after 15 mins by flow cytometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4022973
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 306.37 | 3.47 | 3.47 |
| 371.43 | 1.10 | 1.10 |
| 363.37 | 1.41 | 1.41 |
| 323.42 | 1.25 | 1.25 |
| 337.45 | 1.50 | 1.50 |
| 351.43 | 0.49 | 0.49 |
| 335.43 | 1.25 | 1.25 |
| 350.45 | 0.76 | 0.76 |
| 363.45 | 0.60 | 0.60 |
| 336.46 | 2.39 | 2.39 |
| 321.41 | 1.01 | 1.01 |
| 337.45 | 1.50 | 1.50 |
| 350.45 | 0.85 | 0.85 |
| 339.42 | 0.49 | 0.49 |
| 365.50 | 2.23 | 2.23 |
| 349.46 | 1.50 | 1.50 |
| 349.46 | 1.64 | 1.64 |
| 324.41 | 0.37 | 0.37 |
| 320.42 | 1.75 | 1.75 |
| 364.48 | 1.25 | 1.25 |
| 336.42 | 0.51 | 0.51 |
| 391.42 | 2.19 | 2.19 |
| 363.45 | 0.65 | 0.65 |
| 371.47 | 2.04 | 2.04 |
| 338.44 | 0.71 | 0.71 |
| 353.45 | 0.88 | 0.88 |
| 337.45 | 1.64 | 1.64 |
| 323.42 | 1.11 | 1.11 |
| 322.43 | 2.00 | 2.00 |
| 309.40 | 0.86 | 0.86 |
| 351.48 | 1.89 | 1.89 |
| 363.49 | 1.84 | 1.84 |
| 338.44 | 0.76 | 0.76 |
| 348.43 | 1.15 | 1.15 |
| 308.41 | 1.61 | 1.61 |
| 295.37 | 0.47 | 0.47 |
| 357.44 | 1.90 | 1.90 |
| 323.42 | 1.25 | 1.25 |
| 377.39 | 1.80 | 1.80 |
| 356.45 | 2.65 | 2.65 |
| 375.43 | 2.04 | 2.04 |
| 349.46 | 1.60 | 1.60 |