Basic Information
ID: ALA4023009
Type: Binding
Description: Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IL-10 induced STAT3 phosphorylation preincubated for 45 mins followed by IL-10 addition measured after 15 mins by flow cytometric analysis
Format: BAO_0000223
Organism: Homo sapiens
Target: JAK1/TYK2(ALA3301391)
Document: ALA4020822
Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IL-10 induced STAT3 phosphorylation preincubated for 45 mins followed by IL-10 addition measured after 15 mins by flow cytometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4023009
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.42 | 1.25 | 1.25 |