Assay Report Card

Basic Information

ID: ALA4023968

Type: ADME

Description: Substrate activity at human OAT3 expressed in HEK293 cells assessed as ratio of compound uptake in human OAT3 transfected HEK293 cells to uptake in vector-treated HEK293 cells at 1 uM after 3 mins by LC-MS analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
341.794.564.56
414.894.294.29
331.763.563.56
325.344.044.04
332.363.783.78
343.334.184.18
355.825.435.43
345.784.214.21
345.793.663.66
357.365.055.05
332.743.603.60
302.723.593.59
315.763.653.65
357.365.055.05