Assay Report Card

Basic Information

ID: ALA4023970

Type: ADME

Description: Substrate activity at human OAT1 expressed in HEK293 cells assessed as ratio of compound uptake in human OAT1 transfected HEK293 cells to uptake in vector-treated HEK293 cells at 1 uM after 3 mins by LC-MS analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
341.794.564.56
414.894.294.29
331.763.563.56
325.344.044.04
345.793.663.66
357.365.055.05