Basic Information
ID: ALA4024007
Type: Binding
Description: Inhibition of RIPK1 in mouse L929 cells assessed as decrease in TNFalpha/zVAD-FMK-induced MLKL phosphorylation at S358 residue preincubated for 30 mins followed by TNFalpha/zVAD-FMK addition measured after 6 hrs by sandwich ELISA
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4024007
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.91 | 2.88 | 2.88 |