Basic Information
ID: ALA4024626
Type: Binding
Description: Inhibition of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid binding to human full length His/MBP-fused TNNI3K expressed in baculovirus expression system after 60 mins by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4024626
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 304.34 | 1.00 | 1.00 |
| 303.35 | 1.61 | 1.61 |
| 432.94 | 3.59 | 3.59 |
| 487.89 | 4.47 | 4.47 |
| 403.90 | 3.83 | 3.83 |
| 407.86 | 3.66 | 3.66 |
| 389.87 | 3.53 | 3.53 |
| 473.86 | 4.42 | 4.42 |
| 424.31 | 4.18 | 4.18 |
| 435.96 | 4.25 | 4.25 |
| 419.89 | 3.53 | 3.53 |
| 418.91 | 3.57 | 3.57 |
| 368.46 | 3.79 | 3.79 |
| 390.86 | 2.92 | 2.92 |
| 389.87 | 3.53 | 3.53 |
| 390.86 | 2.92 | 2.92 |
| 474.85 | 3.82 | 3.82 |
| 373.41 | 3.01 | 3.01 |
| 400.42 | 2.78 | 2.78 |
| 370.44 | 2.58 | 2.58 |
| 355.42 | 2.87 | 2.87 |
| 497.00 | 3.10 | 3.10 |
| 385.45 | 2.88 | 2.88 |
| 383.48 | 3.20 | 3.20 |
| 468.95 | 2.32 | 2.32 |
| 411.53 | 4.17 | 4.17 |
| 369.45 | 3.18 | 3.18 |
| 433.52 | 2.28 | 2.28 |
| 385.45 | 2.88 | 2.88 |
| 397.50 | 4.00 | 4.00 |
| 293.35 | 1.17 | 1.17 |
| 369.45 | 3.18 | 3.18 |
| 383.48 | 3.20 | 3.20 |
| 488.88 | 3.86 | 3.86 |
| 511.03 | 3.49 | 3.49 |
| 434.32 | 3.63 | 3.63 |
| 482.98 | 2.71 | 2.71 |
| 369.45 | 3.18 | 3.18 |
| 433.52 | 2.28 | 2.28 |
| 424.41 | 3.29 | 3.29 |
| 420.88 | 2.93 | 2.93 |
| 423.42 | 3.89 | 3.89 |
| 385.45 | 2.88 | 2.88 |
| 369.45 | 3.18 | 3.18 |
| 448.53 | 1.78 | 1.78 |