Basic Information
ID: ALA4024933
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as substrate pretreated for 60 mins followed by substrate addition after 1 hr by ADP-Glo luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4024933
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.51 | 4.22 | 4.22 |
| 499.51 | 4.77 | 4.77 |
| 560.54 | 6.18 | 6.18 |
| 423.45 | 4.25 | 4.25 |
| 447.50 | 4.01 | 4.01 |
| 647.78 | 6.25 | 6.25 |
| 634.74 | 5.02 | 5.02 |
| 651.79 | 5.89 | 5.89 |