Basic Information
ID: ALA4025643
Type: ADME
Description: Prodrug activation in mouse liver microsomes assessed as CYP450 reductase-mediated SN-38 release at 5 uM after 6 hrs in presence of NADPH by HPLC method
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4025643
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 689.68 | 2.98 | 2.98 |
| 531.53 | 2.86 | 2.86 |