Basic Information
ID: ALA4025651
Type: Binding
Description: Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mins followed by substrate and cofactor addition after 60 mins by LC/MS analysis
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA4025651
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.52 | 5.40 | 5.40 |
| 312.41 | 4.30 | 4.30 |
| 328.41 | 4.00 | 4.00 |
| 296.39 | 3.56 | 3.56 |
| 287.36 | 3.32 | 3.32 |
| 316.38 | 4.13 | 4.13 |
| 298.39 | 3.99 | 3.99 |