Assay Report Card

Basic Information

ID: ALA4026427

Type: ADME

Description: Agonist activity at NLRP3 in human THLP1-null cells assessed as induction of LPS-induced IL-1beta secretion by HEK-Blue reporter cell based assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
507.18-1.63-1.63
492.48-4.33-4.33
887.131.711.71
1090.32
1088.43
758.952.492.49
1258.64
620.66-4.71-4.71
920.11-0.11-0.11
927.287.037.03
1055.45