Basic Information
ID: ALA4026494
Type: Binding
Description: Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in presence of [3H]SAM by microbeta counting method
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4026494
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.53 | 4.98 | 4.98 |
| 346.45 | 2.23 | 2.23 |
| 310.44 | 3.35 | 3.35 |
| 286.44 | 3.49 | 3.49 |
| 334.92 | 4.48 | 4.48 |
| 320.89 | 4.14 | 4.14 |
| 324.34 | 2.93 | 2.93 |
| 336.50 | 4.64 | 4.64 |
| 304.43 | 3.63 | 3.63 |
| 320.89 | 4.14 | 4.14 |
| 300.47 | 3.83 | 3.83 |
| 334.87 | 3.78 | 3.78 |
| 306.86 | 3.88 | 3.88 |
| 300.43 | 3.13 | 3.13 |
| 318.46 | 3.97 | 3.97 |
| 404.49 | 5.83 | 5.83 |
| 350.49 | 4.28 | 4.28 |
| 318.42 | 3.27 | 3.27 |