Basic Information
ID: ALA4026559
Type: Binding
Description: Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 mins by TopCount microscintillation counting assay
Format: BAO_0000249
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsomal Membrane
Target: Fatty acid desaturase 1(ALA5727)
Document: ALA4024749
Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 mins by TopCount microscintillation counting assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4026559
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.29 | 3.53 | 3.53 |
| 310.33 | 4.17 | 4.17 |
| 338.19 | 4.39 | 4.39 |
| 321.31 | 3.66 | 3.66 |
| 282.27 | 3.40 | 3.40 |
| 340.18 | 4.83 | 4.83 |
| 296.30 | 3.78 | 3.78 |
| 296.30 | 3.78 | 3.78 |
| 323.18 | 3.40 | 3.40 |
| 296.30 | 3.78 | 3.78 |
| 329.35 | 2.70 | 2.70 |
| 275.25 | 3.66 | 3.66 |
| 282.27 | 3.40 | 3.40 |
| 330.75 | 4.44 | 4.44 |
| 257.26 | 3.52 | 3.52 |
| 282.27 | 3.40 | 3.40 |
| 317.32 | 3.54 | 3.54 |
| 388.85 | 3.23 | 3.23 |
| 324.40 | 4.63 | 4.63 |
| 314.29 | 3.92 | 3.92 |
| 291.71 | 4.18 | 4.18 |