Basic Information
ID: ALA4026560
Type: Binding
Description: Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid addition measured after 3 hrs by TLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4026560
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.29 | 3.53 | 3.53 |
| 310.33 | 4.17 | 4.17 |
| 338.19 | 4.39 | 4.39 |
| 321.31 | 3.66 | 3.66 |
| 282.27 | 3.40 | 3.40 |
| 340.18 | 4.83 | 4.83 |
| 296.30 | 3.78 | 3.78 |
| 296.30 | 3.78 | 3.78 |
| 323.18 | 3.40 | 3.40 |
| 296.30 | 3.78 | 3.78 |
| 275.25 | 3.66 | 3.66 |
| 282.27 | 3.40 | 3.40 |
| 330.75 | 4.44 | 4.44 |
| 257.26 | 3.52 | 3.52 |
| 282.27 | 3.40 | 3.40 |
| 317.32 | 3.54 | 3.54 |
| 388.85 | 3.23 | 3.23 |
| 314.29 | 3.92 | 3.92 |
| 291.71 | 4.18 | 4.18 |