Reactivation of cyclosarin inhibited human erythrocyte AChE assessed as residual activity at 10 to 1000 uM using acetylthiocholine iodide as substrate...

Basic Information

ID: ALA4026840

Type: Binding

Description: Reactivation of cyclosarin inhibited human erythrocyte AChE assessed as residual activity at 10 to 1000 uM using acetylthiocholine iodide as substrate preincubated for 2 to 120 mins followed by substrate addition measured for 3 mins by Ellman's method

Format: BAO_0000357

Organism: Homo sapiens

Target:  Acetylcholinesterase(ALA220)

Document:  ALA4024757

Reactivation of cyclosarin inhibited human erythrocyte AChE assessed as residual activity at 10 to 1000 uM using acetylthiocholine iodide as substrate preincubated for 2 to 120 mins followed by substrate addition measured for 3 mins by Ellman's method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
137.181.151.15
73.140.750.75
172.620.320.32
359.210.510.51
30.03-0.18-0.18
392.460.900.90
69.111.311.31
261.07-0.13-0.13
169.14-0.22-0.22
157.050.460.46
479.381.341.34
307.351.011.01
225.251.341.34
359.21-0.20-0.20
420.511.691.69
174.16-0.57-0.57
197.190.560.56
174.16-0.57-0.57
89.05-0.47-0.47
406.481.291.29
317.181.431.43
321.381.401.40
443.552.812.81
103.08-0.08-0.08
535.482.902.90
392.460.900.90
202.210.210.21
75.11-0.41-0.41
188.18-0.18-0.18
114.06-0.58-0.58