Basic Information
ID: ALA4026921
Type: ADME
Description: Inhibition of N-terminal His-tagged human beta-glucuronidase expressed in Escherichia coli BL21 (DE3) assessed as residual activity using pNPG as substrate at 10 uM preincubated for 30 mins followed by substrate addition measured after 1 hr relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4026921
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 192.12 | -2.92 | -2.92 |
| 455.51 | 3.38 | 3.38 |
| 314.34 | 5.14 | 5.14 |
| 425.55 | 3.73 | 3.73 |
| 344.20 | 4.74 | 4.74 |
| 293.30 | 3.58 | 3.58 |
| 309.76 | 4.09 | 4.09 |
| 289.34 | 3.75 | 3.75 |
| 380.40 | 4.37 | 4.37 |
| 368.24 | 4.51 | 4.51 |
| 390.49 | 3.86 | 3.86 |
| 289.34 | 3.75 | 3.75 |
| 343.31 | 4.46 | 4.46 |
| 323.79 | 4.40 | 4.40 |
| 257.27 | 1.26 | 1.26 |
| 291.31 | 3.14 | 3.14 |
| 319.32 | 3.14 | 3.14 |
| 228.25 | 2.09 | 2.09 |
| 383.40 | 6.03 | 6.03 |
| 540.61 | 3.18 | 3.18 |
| 320.31 | 3.35 | 3.35 |
| 285.33 | 1.94 | 1.94 |
| 385.46 | 3.90 | 3.90 |
| 309.76 | 4.09 | 4.09 |
| 303.37 | 4.05 | 4.05 |
| 200.20 | 1.40 | 1.40 |
| 248.29 | 1.54 | 1.54 |
| 275.32 | 3.44 | 3.44 |
| 317.35 | 3.64 | 3.64 |
| 504.63 | 5.32 | 5.32 |
| 388.66 | 4.85 | 4.85 |
| 291.31 | 3.14 | 3.14 |
| 360.37 | 2.97 | 2.97 |
| 309.76 | 4.09 | 4.09 |
| 290.33 | 3.02 | 3.02 |
| 307.33 | 3.88 | 3.88 |
| 274.28 | 2.70 | 2.70 |
| 199.22 | 1.28 | 1.28 |
| 383.40 | 6.03 | 6.03 |
| 528.63 | 5.33 | 5.33 |
| 327.75 | 4.23 | 4.23 |
| 332.31 | 2.49 | 2.49 |
| 533.63 | 4.87 | 4.87 |
| 359.43 | 3.36 | 3.36 |
| 184.20 | 1.69 | 1.69 |
| 291.31 | 3.14 | 3.14 |
| 330.39 | 3.41 | 3.41 |
| 210.19 | 3.12 | 3.12 |
| 323.79 | 4.40 | 4.40 |
| 371.44 | 3.51 | 3.51 |
| 289.34 | 3.75 | 3.75 |
| 363.41 | 4.25 | 4.25 |