Assay Report Card

Basic Information

ID: ALA4026936

Type: Binding

Description: Proteolysis targeting chimera activity in human THP1 cells assessed as induction of VHL-mediated delivery of RIPK2 for protein degradation by proteasome by measuring drug level causing 50% cellular protein depletion incubated for 16 hrs by Western blotting method

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1060.33