Assay Report Card

Basic Information

ID: ALA4027105

Type: Unassigned

Description: Time at which plasma concentration stays above cellular IRAK4 IC50 in SCID CB.17 mouse xenografted with human OCI-LY10 cells at 12.5 mg/kg, po qd cotreated with ibrutinib measured after 7 days by LC-MS analysis

Organism: Mus musculus

Strain: CB.17

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
385.512.912.91