Basic Information
ID: ALA4027117
Type: Binding
Description: Antagonist activity at rat alpha4beta2 nAChR expressed in HEK cells assessed as inhibition of epibatidine-induced membrane potential preincubated for 10 mins followed by epibatidine addition by fluorescence assay
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Neuronal acetylcholine receptor; alpha4/beta2(ALA1907596)
Document: ALA4024764
Antagonist activity at rat alpha4beta2 nAChR expressed in HEK cells assessed as inhibition of epibatidine-induced membrane potential preincubated for 10 mins followed by epibatidine addition by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4027117
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 220.28 | -0.18 | -0.18 |
| 204.28 | 0.85 | 0.85 |