Basic Information
ID: ALA4027180
Type: Binding
Description: Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate after 90 mins by fluorimetric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4027180
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.33 | 2.82 | 2.82 |
| 256.26 | 2.06 | 2.06 |
| 273.29 | 2.39 | 2.39 |
| 323.35 | 2.97 | 2.97 |
| 260.27 | 2.56 | 2.56 |
| 306.37 | 3.88 | 3.88 |
| 304.73 | 3.02 | 3.02 |
| 276.72 | 3.07 | 3.07 |
| 302.33 | 2.43 | 2.43 |
| 320.78 | 3.64 | 3.64 |
| 307.73 | 3.05 | 3.05 |
| 332.40 | 4.39 | 4.39 |
| 270.33 | 2.98 | 2.98 |
| 307.73 | 3.05 | 3.05 |
| 325.19 | 4.03 | 4.03 |
| 286.33 | 2.47 | 2.47 |
| 364.40 | 4.22 | 4.22 |
| 346.60 | 4.34 | 4.34 |
| 312.15 | 3.69 | 3.69 |
| 290.75 | 3.38 | 3.38 |
| 325.19 | 4.03 | 4.03 |
| 325.15 | 3.36 | 3.36 |
| 270.33 | 2.77 | 2.77 |
| 306.75 | 3.08 | 3.08 |
| 320.73 | 2.72 | 2.72 |
| 342.18 | 3.70 | 3.70 |
| 290.75 | 3.38 | 3.38 |
| 284.36 | 3.16 | 3.16 |
| 256.31 | 2.73 | 2.73 |
| 312.15 | 3.69 | 3.69 |
| 272.30 | 2.43 | 2.43 |